Pellino 1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Pellino 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Pellino 1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Pellino 1 from other sources has not been determined. The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-kB. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-e and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation. |
| Immunogen | Anti- Pellino 1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the C-terminus of human Pellino 1. |
| Other Names | Pellino 1 Antibody, PRISM, E3 ubiquitin-protein ligase pellino homolog 1, Pellino-related intracellular-signaling molecule, Pellino-1 |
| Gene, Accession # | PELI1, Gene ID: 57162, NCBI: NP_065702, UniProt: Q96FA3 |
| Catalog # | 600-401-DL0 |
| Price | $475 |
| Order / More Info | Pellino 1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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