Edit |   |
---|---|
Antigenic Specificity | COBRA 1 |
Clone | F7E4 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µL |
Concentration | Titrated value sufficient to run approximately 10 mini blots. |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-COBRA 1 antibody was Protein G purified from culture supernatant. This antibody is directed against human COBRA 1. Reactivity is expected against mouse and rat sources. Cross-reactivity from other sources has not been determined. COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli. |
Other Names | COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1 |
Gene, Accession # | NELFB, Gene ID: 25920, UniProt: Q8WX92 |
Catalog # | 200-301-D18 |
Price | $485 |
Order / More Info | COBRA 1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |