ZIC-2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityZIC-2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Western Blot
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DescriptionThis affinity purified antibody is directed against mouse ZIC2 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, chimpanzee, mouse, rat and dog based on 100% homology for the immunogen sequence. Expect cross reactivity with ZIC2 from chicken, zebrafish and frog as the core 16 amino acid residues within the immunogen sequence show very high degrees of homology with ZIC2 from these sources. Cross reactivity with ZIC2 homologues from other sources has not been determined. ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 180-210 of Mouse ZIC-2.
Other Namesrabbit anti-ZIC-2 antibody, ZIC 2, ZIC2, zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog
Gene, Accession #Zic2 UniProt: Q62520
Catalog #600-401-848
Price$475
Order / More InfoZIC-2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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