SRPX1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | SRPX1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-SRPX1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SRPX1 from other sources has not been determined. SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy. |
| Immunogen | Anti-SRPX1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide from near the N-terminus of human SRPX1. |
| Other Names | SRPX1 Antibody, DRS, ETX1, SRPX1, HEL-S-83p, Sushi repeat-containing protein SRPX |
| Gene, Accession # | SRPX, Gene ID: 8406, NCBI: NP_001164221.1, UniProt: P78539 |
| Catalog # | 600-401-EV0 |
| Price | $475 |
| Order / More Info | SRPX1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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