CD11b Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD11b |
| Clone | ICRF44 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µL |
| Concentration | n/a |
| Applications | Flow Cytometry, IF Microscopy, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD11b Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11b. Reactivity is observed against human CD11b, Chimpanzee, Baboon, Cynomolgus, Rhesus, Common Marmoset, and Swine. Cross reactivity with CD11b from other sources has not been tested. Anti-CD11b is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and Factor X. |
| Immunogen | Anti-CD11b Antibody (Monoclonal) was produced by repeated immunizations with CD11b antigen. |
| Other Names | Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, CR3A |
| Gene, Accession # | ITGAM, Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
| Catalog # | 200-302-N20 |
| Price | $495 |
| Order / More Info | CD11b Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 32565871 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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