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Antigenic Specificity | JMJD2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | 0.66 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-JMJD2a Antibody was purified by affinity purification. Cross reactivity with other species was not tested. JMJD2a, belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Anti-JMJD2a Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics. |
Immunogen | Anti-JMJD2a Antibody was produced in rabbits by repeated immunizations with a synthetic peptide from human JMJD2a containing a sequence from the internal part of the protein. |
Other Names | Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, JHDM3A, JMJD2, KIAA0677 |
Gene, Accession # | KDM4A, Gene ID: 9682, NCBI: NP_055478.2, UniProt: O75164 |
Catalog # | 600-401-X45 |
Price | $445 |
Order / More Info | JMJD2A Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |