DELE Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | DELE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-DELE Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DELE from other sources has not been determined. DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-a and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-a, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors. |
| Immunogen | Anti-DELE antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human DELE. |
| Other Names | DELE Antibody, Death ligand signal enhancer, DAP3-binding cell death enhancer 1, KIAA0141, DELE1 |
| Gene, Accession # | DELE1, Gene ID: 9812, NCBI: NP_055588, UniProt: Q14154 |
| Catalog # | 600-401-AU8 |
| Price | $475 |
| Order / More Info | DELE Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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