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Antigenic Specificity | CASPR2 |
Clone | S67-25 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CASPR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to CASPR/Paranodin. Cross-reactivity with CASPR2 from other sources has not been determined. Scaffolds research. Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B. |
Immunogen | CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2. |
Other Names | Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868 |
Gene, Accession # | CNTNAP2, Gene ID: 26047, NCBI: NP_054860.1, UniProt: Q9UHC6 |
Catalog # | 200-301-F04 |
Price | $485 |
Order / More Info | CASPR2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |