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Antigenic Specificity | SARS-CoV-2 Spike Protein (RBD) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | SARS-CoV-2 |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 25 µL |
Concentration | 0.99 mg/mL |
Applications | ELISA, IF Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SARS-CoV-2 Spike affinity purified antibody is directed against SARS Coronavirus 2 Spike protein. The product was purified from monospecific antiserum by immunoaffinity chromatography over SARS CoV-2 Spike resin. BLAST analysis was used to suggest reactivity with related Coronavirus proteins. Cross reactivity with homologues from other sources has not been determined. SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) the virus that causes the disease COVID-19, is related to SARS-CoV, MERS-CoV, and other betacoronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive strand RNA virus that consists of several structural proteins including spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein; and other non-structural proteins (NSPs). Spike proteins located on the surface of the virus, have a high affinity for binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial which serves as an entry mechanism for infection. As such, the S protein may be vital to blocking viral infection and vaccine development. Anti-SARS-CoV-2 Spike Protein Antibody is useful for researchers interested in diagnostics, vaccines, and viral research. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the SARS Coronavirus Spike Protein within the Receptor Binding Domain (RBD). |
Other Names | rabbit anti-SARS CoV 2 Spike Protein Receptor Binding Domain Antibody, Spike glycoprotein antibody, SARS CoV2 antibody, 2019-nCoV, COVID-19, S glycoprotein, Severe acute respiratory syndrome antibody, Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) |
Gene, Accession # | S NCBI: MN908947.3, UniProt: P0DTC2 |
Catalog # | 600-401-MS8S |
Price | $125 |
Order / More Info | SARS-CoV-2 Spike Protein (RBD) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 34297470 // 34737266 // 35241661 |