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Antigenic Specificity | ASAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 25 µL |
Concentration | 1.04 mg/ml |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity purified antibody is directed against human ASAP1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity to human 100%, bovine 93%, and rat and mouse 87% homology for the immunogen sequence. Cross-reactivity from other sources has not been determined. This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1) is a Protein Coding gene. This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. ASAP1 may function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity) and plays a role in ciliogenesis. Anti-ASAP1 is useful for researchers interested in GTPase activities and EGFR1 Signaling Pathway. |
Immunogen | Anti-ASAP1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the c-terminus region of human ASAP1 protein. |
Other Names | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, DEF-1, Differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP |
Gene, Accession # | ASAP1, Gene ID: 50807, NCBI: NP_001234925.1, UniProt: Q9ULH1 |
Catalog # | 600-401-GY1S |
Price | $125 |
Order / More Info | ASAP1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |