TLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TLR4 |
| Clone | MTS510 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | Protein G purified, no preservative |
| Size | 100 µg |
| Concentration | 0.5 mg/mL |
| Applications | Flow Cytometry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-TLR4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR4 from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR4 from other sources has not been determined. Toll Like Receptors and signaling research. Anti-TLR4 CD284 Antibody detects human TLR4. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Among this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling. The TLR4 cDNA codes for a protein consisting of 799 amino acids with approximate molecular weight of 88 kDa. Anti-TLR4 CD284 Antibody is ideal for investigators involved in cytokines and growth factor research. |
| Immunogen | TLR4 Antibody was produced in rats prepared by repeated immunizations with the Ba/F3 cell line expressing mouse protein TLR4. |
| Other Names | hToll, Toll-like receptor 4, CD284 |
| Gene, Accession # | Tlr4, Gene ID: 21898, NCBI: NP_067272.1, UniProt: Q9QUK6 |
| Catalog # | 200-501-I26 |
| Price | $495 |
| Order / More Info | TLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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