Edit |   |
---|---|
Antigenic Specificity | CRIM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CRIM1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. CRIM1 antibody is human reactive. CRIM1 antibody is predicted to not cross-react with CRIM2. CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival. |
Immunogen | Anti-CRIM1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human Crim1. |
Other Names | CRIM1 Antibody, S52, CRIM-1, S52, UNQ1886/PRO4330, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52 |
Gene, Accession # | CRIM1, Gene ID: 51232, NCBI: NP_057525, UniProt: Q9NZV1 |
Catalog # | 600-401-AN3 |
Price | $475 |
Order / More Info | CRIM1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |