Edit |   |
---|---|
Antigenic Specificity | West Nile Virus Matrix |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-West Nile Virus Matrix Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with West Nile Virus Matrix from other sources has not been determined. West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin. |
Immunogen | Anti-West Nile virus matrix antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to 15 amino acids near the internal region of the west nile virus matrix precursor protein. |
Other Names | West Nile Virus Matrix Antibody, Genome polyprotein, Core protein, NS1 |
Gene, Accession # | WNVgp1, Gene ID: 912267, NCBI: NP_776012, UniProt: P06935 |
Catalog # | 600-401-FY7 |
Price | $475 |
Order / More Info | West Nile Virus Matrix Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |