LMP-1 (Epstein-Barr Virus) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | LMP-1 (Epstein-Barr Virus) |
| Clone | CS1, CS2, CS3, CS4 |
| Host Species | Mouse |
| Reactive Species | Epstein-Barr Virus |
| Isotype | IgG1 |
| Format | supernatant |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody was clarified from tissue culture supernatant. This antibody is specific to 60 kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. Latent membrane protein 1 acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. It functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. It interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins. For example, LMP1 induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses. |
| Immunogen | Anti-LMP-1 (Epstein-Barr Virus) antibody was produced in mice by repeated immunizations with recombinant fusion protein containing sequences of bacterial β-galactosidase and EBV encoded latent membrane protein. |
| Other Names | Epstein-Barr Virus, EBV, Latent Membrane Protein 1, Human herpesvirus 4, HHV-4 |
| Gene, Accession # | EBV |
| Catalog # | Mob194-01 |
| Price | $485 |
| Order / More Info | LMP-1 (Epstein-Barr Virus) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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