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Antigenic Specificity | c-Myc |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | 85 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antiserum is directed against human c-myc and is useful in determining its presence in various assays. Anti-c-myc is highly specific for c-myc and shows no cross-reaction with N-myc or L-myc proteins. c-myc is involved in the control of cell proliferation and differentiation at the transition from S --> G1 phase for a normal cell. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (k light chain); or 22 (l light chain) is described in Burkitt's lymphoma and other B-cell lympho-proliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms. Abnormal expression can take many forms including transduction, insertional activation, translocation, and amplification. |
Immunogen | This whole rabbit serum was prepared by repeated immunizations with c-myc peptide corresponding to amino acids KHKLEQLRNSGA which map to the last 12 amino acids of the mouse |
Other Names | rabbit anti-c-Myc Antibody, Myc proto-oncogene protein antibody, Proto-oncogene c-Myc antibody, Transcription factor p64 antibody, Class E basic helix-loop-helix protein 39 antibody, Proto-oncogene c-Myc |
Gene, Accession # | c-Myc, Gene ID: 17869, NCBI: NP_001170823.1, UniProt: P01108 |
Catalog # | 100-401-224 |
Price | $475 |
Order / More Info | c-Myc Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |