APAF1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | APAF1 |
| Clone | 2E10 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apaf1 Antibody is directed against human Apaf1 protein. The product was purified from Ascites by immunoaffinity chromatography purified IgG. Expect reactivity with human, mouse and rat Apaf1. Cross-reactivity with Apaf1 from other sources has not been determined. Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. The mammalian homologue of the key cell death gene CED-4 in C. elegans was identified recently from human and mouse and designated Apaf1 for apoptosis protease-activating factor 1. Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3, one of the key proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Apaf1 transcript is ubiquitously expressed in human tissues. Anti-Apaf1 antibody is ideal for investigators that are involved in Apoptosis, Cytokine and growth factor research. |
| Immunogen | Anti-Apaf1 Antibody monoclonal antibody was prepared using conventional hybridoma technology after repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human Apaf1 protein. |
| Other Names | Apoptotic peptidase activating factor 1 antibody, Apoptotic protease activating factor 1 antibody, Apoptotic protease activating factor antibody, CED 4 antibody, CED4 antibody, KIAA0413 antibody, Apaf1, Apaf-1 |
| Gene, Accession # | APAF1, Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727 |
| Catalog # | 200-301-A35 |
| Price | $485 |
| Order / More Info | APAF1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
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