Edit |   |
---|---|
Antigenic Specificity | IRF2BP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IRF2BP2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of IRF2BP2 are known to exist; this antibody will detect both. IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation. |
Immunogen | Anti-IRF2BP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 17 amino acid synthetic peptide near the N-terminus of human IRF2BP2. |
Other Names | IRF2BP2 Antibody, Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2 |
Gene, Accession # | IRF2BP2, Gene ID: 359948, NCBI: NP_892017, UniProt: Q7Z5L9 |
Catalog # | 600-401-BZ9 |
Price | $475 |
Order / More Info | IRF2BP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |