IRF2BP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIRF2BP2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry
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DescriptionAnti-IRF2BP2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of IRF2BP2 are known to exist; this antibody will detect both. IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.
ImmunogenAnti-IRF2BP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 17 amino acid synthetic peptide near the N-terminus of human IRF2BP2.
Other NamesIRF2BP2 Antibody, Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2
Gene, Accession #IRF2BP2, Gene ID: 359948, NCBI: NP_892017, UniProt: Q7Z5L9
Catalog #600-401-BZ9
Price$475
Order / More InfoIRF2BP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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