IL-15 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | IL-15 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-IL-15 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of IL-15 are known to exist. Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. |
| Immunogen | Anti- IL-15 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid peptide near the internal region of human IL-15. |
| Other Names | IL-15 Antibody, IL-15, Interleukin-15, IL-15 |
| Gene, Accession # | IL15, Gene ID: 3600, NCBI: NP_000576, UniProt: P40933 |
| Catalog # | 600-401-BU3 |
| Price | $475 |
| Order / More Info | IL-15 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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