TIRAP Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TIRAP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-TIRAP Antibody was purified from monospecific antiserum. This product is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross-reactivity with TIRAP with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with TIRAP from other sources has not been determined. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP (Toll-interleukin 1 receptor domain-containing adaptor protein) and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 or TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-kB and MAP kinase activation, suggesting that TIRAP is also involved in TLR4 signaling. Anti-TIRAP antibody is ideal for investigators involved cytokines and growth factors research. |
| Immunogen | TIRAP Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of mouse TIRAP. |
| Other Names | Adapter protein wyatt antibody, FLJ42305 antibody, MAL antibody, MyD88 adapter like protein antibody, TIR domain containing adapter protein antibody, Toll interleukin 1 receptor (TIR) domain containing adaptor protein antibody |
| Gene, Accession # | TIRAP, Gene ID: 117149, NCBI: NP_001171318.1, UniProt: Q99JY1 |
| Catalog # | 200-401-A67 |
| Price | $475 |
| Order / More Info | TIRAP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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