Trail Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTrail
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsImmunohistochemistry, Western Blot
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DescriptionAnti-Trail Antibody is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross-reactivity with Trail with Human based on 100% homology with the immunizing sequence. Cross-reactivity with Trail from other sources has not been determined. Trail Antibody detects cytokines in the TNF family. Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand)1, TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells. Anti-Trail antibodies are ideal for investigators involved in Cytokines and Growth Factors and Apoptosis research.
ImmunogenTrail Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human TRAIL.
Other NamesApo-2L, TRAIL
Gene, Accession #TNFSF10, Gene ID: 8743, NCBI: NP_003801, UniProt: P50591
Catalog #200-401-H27
Price$475
Order / More InfoTrail Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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