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Antigenic Specificity | TWEAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TWEAK Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with TWEAK from other sources has not been determined. TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains. |
Immunogen | Anti-TWEAK antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant human TWEAK. |
Other Names | TWEAK Antibody, APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor necrosis factor ligand superfamily member 12, APO3 ligand |
Gene, Accession # | TNFSF12, Gene ID: 407977, NCBI: NP_003800.1, UniProt: O43508 |
Catalog # | 600-401-FS9 |
Price | $475 |
Order / More Info | TWEAK Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |