CD45RO Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCD45RO
CloneUCHL1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a kappa
Formatfluorescein (FITC) conjugate
Size500 µL
Concentration0.1 mg/mL
ApplicationsFlow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot
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DescriptionFluorescein conjugated CD45RO Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD45RO. Reactivity is observed against human CD45RO. Cross reactivity is observed with Chimpanzee. Reactivity with CD45RO from other sources has not been tested. Anti-CD45RO is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and others.The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.
ImmunogenAnti-CD45RO Antibody (Monoclonal) was produced by repeated immunizations with CD45RO antigen.
Other NamesReceptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, PTPRC , CD45
Gene, Accession #PTPRC, Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575
Catalog #200-302-N71
Price$252
Order / More InfoCD45RO Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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