JMJD1C Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityJMJD1C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-JMJD1C Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody will not cross-react with JMJD1A or JMJD1B. The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
ImmunogenAnti-JMJD1C antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid synthetic peptide from near the N-terminus of human JMJD1C.
Other NamesJMJD1C Antibody, TRIP8, JHDM2C, KIAA1380, TRIP8, Probable JmjC domain-containing histone demethylation protein 2C, Jumonji domain-containing protein 1C, TR-interacting protein 8
Gene, Accession #JMJD1C, Gene ID: 221037, NCBI: NP_116165, UniProt: Q15652
Catalog #600-401-CB5
Price$475
Order / More InfoJMJD1C Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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