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Antigenic Specificity | TIRP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TIRP Antibody is purified by ion exchange chromatography. Cross reactivity with TIRP from other sources has not been determined. TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kB. Expression of TIRP appears to be essential for TLR4 signaling. |
Immunogen | Anti-TIRP antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids at the C-terminus of human TIRP. |
Other Names | TIRP Antibody, TIRP, TRAM, TIRAP3, MyD88-4, TICAM-2, TIRP, TIR domain-containing adapter molecule 2, Putative NF-kappa-B-activating protein 502 |
Gene, Accession # | TICAM2, Gene ID: 100302736, NCBI: NP_001157940.1, UniProt: Q86XR7 |
Catalog # | 200-401-FF4 |
Price | $475 |
Order / More Info | TIRP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |