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Antigenic Specificity | ERRF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ERRF Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ERRF from other sources has not been determined. The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target. |
Immunogen | Anti-ERRF antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the C-terminus of human ERRF. |
Other Names | Steroid receptor-associated and regulated protein, SRARP, ERRF Antibody, ER-related factor, C1orf64, Steroid receptor-regulated protein, SSPR |
Gene, Accession # | SRARP, Gene ID: 149563, NCBI: NP_849162, UniProt: Q8NEQ6 |
Catalog # | 600-401-BB8 |
Price | $475 |
Order / More Info | ERRF Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |