ERRF Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityERRF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-ERRF Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ERRF from other sources has not been determined. The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
ImmunogenAnti-ERRF antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the C-terminus of human ERRF.
Other NamesSteroid receptor-associated and regulated protein, SRARP, ERRF Antibody, ER-related factor, C1orf64, Steroid receptor-regulated protein, SSPR
Gene, Accession #SRARP, Gene ID: 149563, NCBI: NP_849162, UniProt: Q8NEQ6
Catalog #600-401-BB8
Price$475
Order / More InfoERRF Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

Profile of ROCKLAND IMMUNOCHEMICALS INC.

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