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Antigenic Specificity | NALP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NALP10 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NALP10 from other sources has not been determined. NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation. |
Immunogen | Anti-NALP10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the N-terminus of human NALP10. |
Other Names | NALP10 Antibody, NOD8, PAN5, PYNOD, NALP10, CLR11.1, NOD8, NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8 |
Gene, Accession # | NLRP10, Gene ID: 338322, NCBI: NP_789791, UniProt: Q86W26 |
Catalog # | 600-401-CX6 |
Price | $475 |
Order / More Info | NALP10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |