KPNA6 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | KPNA6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-KPNA6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with KPNA6 from other sources has not been determined. Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6. Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation, possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation. KPNA6 also interacts with the Rev protein of HIV-1 and promote its nuclear import. |
| Immunogen | Anti-KPNA6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the N-terminus of human KPNA6. |
| Other Names | KPNA6 Antibody, IPOA7, KPNA7, IPOA7, Importin subunit alpha-7, Karyopherin subunit alpha-6 |
| Gene, Accession # | KPNA6, Gene ID: 23633, NCBI: CAH71948, UniProt: O60684 |
| Catalog # | 600-401-CG5 |
| Price | $475 |
| Order / More Info | KPNA6 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.