Edit |   |
---|---|
Antigenic Specificity | Mdc1 |
Clone | P2B11 |
Host Species | Mouse |
Reactive Species | human, mouse, bovine, chimpanzee |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | IF Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MDC1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with MDC1 from Human, Mouse, Chimpanzee, and Bovine based on 100% homology with the immunizing sequence. This antibody recognizes MDC1 at and around the N-terminus. Cross-reactivity with MDC1 from other sources has not been determined. Oxidative Stress research. MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139. |
Immunogen | MDC1 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to mouse MDC1 at and around the N-terminus region. |
Other Names | Nuclear factor with BRCT domains1, mediator of DNA damage checkpoint 1, Kiaa0170 |
Gene, Accession # | Mdc1, Gene ID: 240087, NCBI: NP_001010833.2, UniProt: Q5PSV9 |
Catalog # | 200-301-G12 |
Price | $485 |
Order / More Info | Mdc1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |