Edit |   |
---|---|
Antigenic Specificity | PIK3R4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-PIK3R4 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PIK3R4 antibody is human, mouse and rat reactive. PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4, also known as VPS15) is a 150kD adaptor protein that enhances the lipid kinase activity of PIK3 complexes and may be involved in regulating membrane trafficking late in the endocytic pathway and autophagy (1,2). PIK3R4 is ubiquitously expressed and contains 7 WD repeats, 3 HEAT repeats and 1 protein kinase domain (1). PIK3R4 is crucial for VPS34 function and is necessary for autophagosome formation in multicellular animals and reveal an important role of VPS15 in cellular protection against ubiquitin-positive protein aggregates (3-5). |
Immunogen | Anti-PIK3R4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human PIK3R4. |
Other Names | Phosphoinositide-3-kinase regulatory subunit 4, p150, Phosphoinositide 3-kinase adaptor protein, PI3-kinase p150 subunit, PI3-kinase regulatory subunit 4, VPS15 |
Gene, Accession # | PIK3R4, Gene ID: 30849, NCBI: NP_055417, UniProt: Q99570 |
Catalog # | 600-401-DN7 |
Price | $475 |
Order / More Info | PIK3R4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |