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Antigenic Specificity | BONZO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Bonzo Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bonzo from other sources has not been determined. Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes. |
Immunogen | Anti-Bonzo antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminus of human Bonzo/STRL33. The sequence of. This peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,. |
Other Names | Bonzo Antibody, BONZO, CD186, STRL33, TYMSTR, BONZO, C-X-C chemokine receptor type 6, CDw186, CXC-R6 |
Gene, Accession # | CXCR6, Gene ID: 10663, NCBI: AAB64221, UniProt: O00574 |
Catalog # | 600-401-Z83 |
Price | $475 |
Order / More Info | BONZO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |