MYCT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityMYCT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-MYCT1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of MYCT1 are known to exist; this antibody will detect both isoforms. MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
ImmunogenAnti-MYCT1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human MYCT1.
Other NamesMYCT1 Antibody, MTLC, MTLC, MTMC1, Myc target protein 1, Myc target in myeloid cells protein 1
Gene, Accession #MYCT1, Gene ID: 80177, NCBI: NP_079383, UniProt: Q8N699
Catalog #600-401-CW4
Price$475
Order / More InfoMYCT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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