P2RX7 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | P2RX7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-P2RX7 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. P2RX7 antibody is human, mouse, and rat reactive. Multiple isoforms of P2RX7 are known to exist. The purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) belongs to the family of purinoceptors for ATP (1). This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules (1,2). Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression (2). Recent studies have suggested that P2RX7 may play a key role in immune-mediated diseases such as rheumatoid arthritis (3) as well as neuropsychiatric disorders (4). |
| Immunogen | Anti-P2RX7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human P2RX7. |
| Other Names | P2X purinoceptor 7, P2X7, purinergic receptor P2X ligand-gated ion channel 7 |
| Gene, Accession # | P2RX7, Gene ID: 5027, NCBI: NP_002553, UniProt: Q99572 |
| Catalog # | 600-401-DH9 |
| Price | $475 |
| Order / More Info | P2RX7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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