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Antigenic Specificity | GZF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GZF1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. GZF1 antibody is human specific. At least four isoforms of GZF1 are known to exist. The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5'regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity. |
Immunogen | Anti-GZF1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the C-terminus of human GZF1. |
Other Names | GZF1 Antibody, ZBTB23, ZNF336, ZBTB23, GDNF-inducible zinc finger protein 1, Zinc finger and BTB domain-containing protein 23 |
Gene, Accession # | GZF1, Gene ID: 64412, NCBI: NP_071927, UniProt: Q9H116 |
Catalog # | 600-401-BP7 |
Price | $475 |
Order / More Info | GZF1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |