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Antigenic Specificity | CD45R (B220) |
Clone | RA3-6B2 |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a kappa |
Format | allophycocyanin (APC) conjugate |
Size | 100 µg |
Concentration | 0.2 mg/ml |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD45R(B220) Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD45R. Cross reactivity is observed with human and Feline. Cross reactivity with CD45R from other sources has not been tested. Anti-CD45R is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
Immunogen | Anti-CD45R (B220) Antibody (Monoclonal) was produced by repeated immunizations with Abelson murine leukemia virus-induced pre-B tumor cells. |
Other Names | Receptor-type tyrosine-protein phosphatase C, , ukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 |
Gene, Accession # | Ptprc UniProt: P06800 |
Catalog # | 200-526-N84 |
Price | $425 |
Order / More Info | CD45R (B220) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |