CD40 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD40 |
| Clone | 5C3 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µL |
| Concentration | n/a |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD40 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD40. Reactivity is observed against human CD40. Cross reactivity is observed with Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus, and Squirrel Monkey. Reactivity with CD40 from other sources has not been tested. Anti-CD40 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
| Immunogen | Anti-CD40 Antibody (Monoclonal) was produced by repeated immunizations with CD40 antigen. |
| Other Names | BP50, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40 |
| Gene, Accession # | CD40, Gene ID: 958, NCBI: NP_001241.1, UniProt: P25942 |
| Catalog # | 200-302-N67 |
| Price | $399 |
| Order / More Info | CD40 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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