LRRTM2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityLRRTM2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-LRRTM2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. LRRTM2 antibody is predicted to not cross-react with other LRRTM family members. The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.
ImmunogenAnti-LRRTM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human LRRTM2.
Other NamesLRRTM2 Antibody, KIAA0416, LRRN2, Leucine-rich repeat transmembrane neuronal protein 2, Leucine-rich repeat neuronal 2 protein
Gene, Accession #LRRTM2, Gene ID: 26045, NCBI: EAW62125, UniProt: O43300
Catalog #600-401-CN0
Price$475
Order / More InfoLRRTM2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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