IL-23 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | IL-23 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-IL-23 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with IL-23 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with IL-23 from other sources has not been determined. IL-23 antibody detects human IL-23. Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer. Anti-IL-23 antibodies are ideal for investigators involved in cytokine and growth factors and cancer research. |
| Immunogen | IL-23 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide near the c-terminus of human IL-23. |
| Other Names | SGRF, IL23A, Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19 |
| Gene, Accession # | IL23A, Gene ID: 51561, NCBI: AAH66268, UniProt: Q9NPF7 |
| Catalog # | 600-401-G99 |
| Price | $475 |
| Order / More Info | IL-23 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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