CD45R (B220) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD45R (B220) |
| Clone | RA3-6B2 |
| Host Species | Rat |
| Reactive Species | human, mouse |
| Isotype | IgG2a kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µg |
| Concentration | 0.5mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD45R (B220) Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD45R. Cross reactivity is observed with human and Feline. Cross reactivity with CD45R from other sources has not been tested. Anti-CD45R is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others. The RA3-6B2 antibody is one of the most consistently used leukocyte markers for B cells, T cell subsets and NK cell subsets in human and mouse. This antibody has also been reported as cross-reactive with feline CD45R/B220. |
| Immunogen | Anti-CD45R (B220) Antibody (Monoclonal) was produced by repeated immunizations with CD45R antigen. |
| Other Names | Receptor-type tyrosine-protein phosphatase C, , ukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 |
| Gene, Accession # | Ptprc UniProt: P06800 |
| Catalog # | 200-502-N84 |
| Price | $399 |
| Order / More Info | CD45R (B220) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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