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Antigenic Specificity | IFIT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IFIT3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family. The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3). |
Immunogen | Anti-IFIT3 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human IFIT3. |
Other Names | IFIT3 Antibody , P60, IRG2, IFI60, IFIT4, ISG60, RIG-G, CIG-49, GARG-49, Interferon-induced protein with tetratricopeptide repeats 3, CIG49, IFIT-3 |
Gene, Accession # | IFIT3, Gene ID: 3437, NCBI: NP_001026853, UniProt: O14879 |
Catalog # | 600-401-BT3 |
Price | $475 |
Order / More Info | IFIT3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |