LANO Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | LANO |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Lano Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Lano from other sources has not been determined. Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues. |
| Immunogen | Anti-Lano antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 15 amino acids near the C-terminus of human Lano. |
| Other Names | LANO Antibody, dJ523E19.1, LANO, Leucine-rich repeat-containing protein 1, LANO adapter protein, LAP and no PDZ protein, LRRC1 |
| Gene, Accession # | LRRC1, Gene ID: 55227, NCBI: AAK72246, UniProt: Q9BTT6 |
| Catalog # | 600-401-CH6 |
| Price | $475 |
| Order / More Info | LANO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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