SYPL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-SYPL2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SYPL2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-SYPL2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1. SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. |
| Immunogen | Anti-SYPL2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human SYPL. |
| Other Names | SYPL2 Antibody, MG29, Synaptophysin-like protein 2 |
| Gene, Accession # | SYPL2, Gene ID: 284612, NCBI: NP_001035799.1, UniProt: Q5VXT5 |
| Catalog # | 600-401-EY9 |
| Price | $475 |
| Order / More Info | SYPL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies