TLR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTLR8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry
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DescriptionAnti-TLR8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.
ImmunogenAnti-TLR8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human TLR8.
Other NamesTLR8 Antibody, CD288, Toll-like receptor 8
Gene, Accession #TLR8, Gene ID: 51311, NCBI: NP_619542.1, UniProt: Q9NR97
Catalog #600-401-FG5
Price$475
Order / More InfoTLR8 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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