NOX3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NOX3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NOX3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins. The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4). |
| Immunogen | Anti-NOX3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the N-terminus of human NOX3. |
| Other Names | NAPDH oxidase 3, NOX-3, GP91-3, MOX2, MOX-2 |
| Gene, Accession # | NOX3, Gene ID: 50508, NCBI: NP_056533, UniProt: Q9HBY0 |
| Catalog # | 600-401-DE0 |
| Price | $475 |
| Order / More Info | NOX3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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