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Antigenic Specificity | Mre11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | S. cerevisiae |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.17 mg/mL |
Applications | ELISA, Chip, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity-purified antibody is directed against Saccharomyces cerevisiae Mre11 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest that little cross reactivity should be expected with this protein from other sources. Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability. Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function. This nuclear protein is widely conserved and is also involved in meiotic double strand break processing. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 575-600 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein. |
Other Names | rabbit anti-Mre11 antibody, Double-strand break repair protein MRE11, DNA recombination and repair protein, Meiotic recombination 11 |
Gene, Accession # | MRE11, Gene ID: 4361, NCBI: 6323880, UniProt: P32829 |
Catalog # | 600-401-872 |
Price | $475 |
Order / More Info | Mre11 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |