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Antigenic Specificity | p90 RSK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity-purified antibody is directed against the human RSK1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross reactivity with RSK1 proteins from human, rat and mouse. Partial reactivity may occur against RSK2 and RSK3 but has not been tested. Reactivity against homologues from other sources is not known. RSK1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsk's appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK1 is studied in cancer research and is known to inactive tumor suppressor complexes and death kinases. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human RSK1 protein. |
Other Names | 90 kDa ribosomal protein S6 kinase 1 antibody, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody, dJ590P13.1 antibody, EC 2.7.11.1 antibody, HU 1 antibody, RSK1 |
Gene, Accession # | RPS6KA1, Gene ID: 6195, NCBI: NP_001006666.1, UniProt: Q15418 |
Catalog # | 600-401-941 |
Price | $475 |
Order / More Info | p90 RSK1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |