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Antigenic Specificity | HSP40 (HDJ1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | 85 mg/mL |
Applications | Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Hsp40 Antibody was prepared from monospecific antiserum by delipidation and defibrination. This polyclonal antibody is specific for human Hsp40 protein. A BLAST analysis was used to suggest cross-reactivity with Hsp40 from Human based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp40 from other sources has not been determined. Heat Shock research. DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ1, is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1. Hsp 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to Hsc70/Hsp70, the mammalian homologues of the bacterial heat shock protein, DnaK. |
Immunogen | Hsp40 Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against recombinant purified human hsp40. |
Other Names | Rabbit anti-Hsp40 Antibody, rabbit anti-heat shock protein 40 antibody, Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1, YDJ1, MAS5, YNL064C, N2418, YNL2418C |
Gene, Accession # | DNAJB1, Gene ID: 3337, NCBI: NP_006136.1, UniProt: P25685 |
Catalog # | 109-401-E57 |
Price | $445 |
Order / More Info | HSP40 (HDJ1) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |