HSP40 (HDJ1) Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityHSP40 (HDJ1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatserum
Size100 µL
Concentration85 mg/mL
ApplicationsImmunoprecipitation, Western Blot
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DescriptionAnti-Hsp40 Antibody was prepared from monospecific antiserum by delipidation and defibrination. This polyclonal antibody is specific for human Hsp40 protein. A BLAST analysis was used to suggest cross-reactivity with Hsp40 from Human based on 100% homology with the immunizing sequence. Cross-reactivity with Hsp40 from other sources has not been determined. Heat Shock research. DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ1, is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1. Hsp 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to Hsc70/Hsp70, the mammalian homologues of the bacterial heat shock protein, DnaK.
ImmunogenHsp40 Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against recombinant purified human hsp40.
Other NamesRabbit anti-Hsp40 Antibody, rabbit anti-heat shock protein 40 antibody, Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1, YDJ1, MAS5, YNL064C, N2418, YNL2418C
Gene, Accession #DNAJB1, Gene ID: 3337, NCBI: NP_006136.1, UniProt: P25685
Catalog #109-401-E57
Price$445
Order / More InfoHSP40 (HDJ1) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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