Cu/Zn SOD Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCu/Zn SOD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, anthozoa, bovine, dog, fish, hamster, invertebrate, mollusk, monkey, mussel, porcine, rabbit, sheep, Xenopus laevis
Isotypen/a
Formataffinity purified
Size100 µg
Concentration1mg/mL
ApplicationsELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
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DescriptionAnti-Cu/Zn SOD Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Cu/Zn SOD from Human, Rat, Mouse, Bovine, Monkey, Invertebrate, Coral (Anthozoa), Dog, Hamster, Pig, Rabbit, Sheep, African clawed frog (Xenopus laevis), Mollusk, Mussel (Perna viridis), Fish (O. melastigma) based on 100% homology with the immunizing sequence. Cross-reactivity with Cu/Zn SOD from other sources has not been determined. Oxidative stress research. Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2? to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.
ImmunogenCu/Zn SOD Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to human Cu/Zn SOD.
Other NamesSuperoxide dismutase1, Superoxide dismutase Cu-Zn, ALS1, IPOA, SOD1, SOD2, SODC, hSod1
Gene, Accession #SOD1, Gene ID: 6647, NCBI: NP_000445.1, UniProt: P00441
Catalog #600-401-F20
Price$455
Order / More InfoCu/Zn SOD Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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