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Antigenic Specificity | GluR2 |
Clone | S21-32 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GluR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with GluR2 from other sources has not been determined. Ion Channels research. The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium. |
Immunogen | GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2. |
Other Names | Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
Gene, Accession # | Gria2, Gene ID: 29627, NCBI: AAA41240.1, UniProt: P19491 |
Catalog # | 200-301-F34 |
Price | $485 |
Order / More Info | GluR2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |