ErpN/OspE Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityErpN/OspE
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesBorrelia burgdorferi
Isotypen/a
FormatProtein A purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Western Blot
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DescriptionThis product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. It is directed against, and shows specific reactivity for, Borrelia burgdorferi OspE protein. Reactivity with ErpN/OspE protein from other sources has not been determined. This product is antibody made against ErpN (OspE/F-Related Protein N), from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. Erp proteins from Borrelia burgdorferi are postulated to be lipoproteins, based on their predicted amino acid sequences. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Several studies have demonstrated that infected humans and animals produce antibodies directed against Erp proteins within the first 2-4 weeks of infection, indicative of Erp synthesis during the initial stages of vertebrate infection. It is postulated that surface-exposed Erp proteins could facilitate interactions with host tissues during the establishment of vertebrate infection.
ImmunogenMBP-fusion protein corresponding to Borrelia burgdorferi ErpN/OspE protein.
Other NamesRabbit anti-ErpN Antibody, rabbit anti-OspE Antibody, rabbit anti-ErpN/OspE Antibody, ErpA, erpA8 protein, outer surface protein E, Borrelia burgdorferi OspE, ospE/F-Related Protein N, BB_L39, cp32-8
Gene, Accession #erpA8, Gene ID: 1194664, NCBI: NP_051416.2, UniProt: H7C7N5
Catalog #200-401-C10
Price$475
Order / More InfoErpN/OspE Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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