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Antigenic Specificity | TSPY1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TSPY1L Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L. Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist. |
Immunogen | Anti- TSPY1L antibody was prepared from whole rabbit serum produced by repeated immunizations with a 20 amino acid peptide near the C-terminus of human TSPY1L. |
Other Names | TSPY1L Antibody, CT78, TSPY, DYS14, pJA923, Testis-specific Y-encoded protein 1, CT78 |
Gene, Accession # | TSPY1, Gene ID: 100289087, NCBI: NP_001071165.2, UniProt: Q01534 |
Catalog # | 600-401-FS1 |
Price | $475 |
Order / More Info | TSPY1L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |